In the past years, several studies have investigated the association of the hOGG1 Ser326Cys polymorphism with HCC risk among East Asians, ,, ,,. Although the evidence is inconclusive that this functional polymorphic variation influences the activity of hOGG1, many epidemiologic studies have been conducted to examine its relationship with cancer risk. It is in exon 7 of the hOGG1 gene, which takes the form of a single amino acid substitution, from serine to cysteine at condon 326. Among many polymorphisms identified in the hOGG1 gene, much interest has been focused on the Ser326Cys (C>G) polymorphism (rs1052133). Polymorphisms in this gene may alter glycosylase function and an individual’s ability to repair damaged DNA, possibly resulting in genetic instability that can foster carcinogenesis. The hOGG1 gene, located on chromosome 3p26.2, is composed of eight exons and seven introns. Human 8-hydroxyguanine glycosylase 1 (hOGG1) is a DNA glycosylase enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. In the past two decades, more and more GWAS (genome-wide association studies) and other gene-disease association studies have found that some variants in human genes are associated with HCC, indicating that genetic background also plays a role in hepatocellular carcinogenesis. Other well-established risk factors for HCC include chronic infection with hepatitis C virus (HCV), exposure to aflatoxin B1, male gender, drinking, smoking, non-alcoholic fatty liver disease and diabetes, ,. The highest prevalence of HCC is in East Asia due to the high prevalence of chronic infection with hepatitis B virus (HBV). Sam Houston Parkway NorthHouston, 77043 Thursday, June 22, 6pm – Thursday, June 29, 2023, 8pm HCC Community Learning Program summer dance classMeets ThursdaysFee: FREEFor registration and details: hccs.Hepatocellular carcinoma (HCC) is the sixth most prevalent cancer and the third most frequent cause of cancer-related death worldwide. We’ll also discuss the importance of business credit and how it differs from your personal credit.Highlights:Steps for building business creditOverview of the major credit reporting agenciesHow to check your business credit reportsUnderstanding business credit scores and ratings including FICO, PAYDEX, and Intelliscore PlusSelecting the right vendors to help build your business creditLeveraging your business creditThis class is intended for new and existing business owners who want to understand the credit process and improve their chances for obtaining business credit.Presenter: Michael SmithRegister now! Participants will receive the Zoom link for the class by email upon registering. You’ll learn about establishing a credit profile, the steps for obtaining an Employer Identification Number (EIN), opening a business bank account, plus much more. Virtual - On Zoom Wednesday, June 21, 2023, 12 – 1:30pm Leveraging Business Credit To Grow Your CompanyDate: Wednesday, June 21stTime: 12:00 PM - 1:30 PMLocation: Virtual - On ZoomJoin us for a comprehensive look at how you can build your business credit. Sam Houston Parkway NorthHouston, 77043 Ongoing through Sunday, July 30, 2023, 5pm HCC Community Learning Program summer dance classClass meets Tuesdays and ThursdaysFee: $89For registration and details: /community-learning Leveraging Business Credit To Grow Your Company – NoonFor registration and details: /community-learning Age 50+ Dance Zumba 12Saturdays10 – 11 a.m.Middle Eastern Belly Dancing II ($89)June 10 – Aug. 8Tuesdays7– 7:55 p.m.Middle Eastern Belly Dancing I ($89)June 10 – Aug. Sam Houston Parkway NorthHouston, 77043 Ongoing through Saturday, August 12, 2023, 8:55pm Teen Ballet ($89)June 5 – Aug. HCC West Houston Institute2811 Hayes RoadHouston, TX 77082 Ongoing through Friday, June 23, 2023, 5pm Summer Dance Classes for Teens & Adults
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